College of Pharmacy and Health Sciences at Mercer University

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Mercer University College of Pharmacy and Health Sciences

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About Us >> Faculty >> Hayslett

Renee Hayslett, Ph.D.

Assistant Professor of Pharmaceutical Sciences

Contact Information
3001 Mercer University Drive, DV-111
Atlanta, GA 30341
(678) 547-6249
Fax: (678) 547-6364
hayslett_rl@mercer.edu

Educational Background
B.A., Spanish, Spelman College
Ph.D., Pharmacology, Howard University

Research Interests

Using animal models to study the pharmacology and behavioral effects of drugs in various disorders of the central nervous system; Investigating the role of receptor systems in mood and movement disorders.

Dr. Hayslett’s broad research interests include discerning neural substrates underlying psychiatric illnesses in order to identify potential therapeutic targets. Her research has focused on Tourette syndrome (TS), a central nervous system disorder that is characterized by persistent motor and phonic tics. Previously, Dr. Hayslett used an animal model of TS in mice to evaluate the efficacy of centrally acting drugs, particularly donepezil, nicotine and haloperidol, in alleviating tic symptoms. She also studied the effects of these drugs on the nicotinic cholinergic and serotonergic receptor systems in order to elucidate the mechanism of action of these drugs in this paradigm.

Dr. Hayslett’s current research focuses on the role of estrogen and nicotinic receptor systems in the pathophysiology of mood disorders, particularly depression. The behavioral effects of agents that modulate these receptor systems are being investigated. In addition, the effects of these drugs on the molecular and cellular regulation of estrogen and nicotinic receptors in discrete brain regions will be explored.

Selected Publications
Hayslett, Renee and Tizabi, Yousef. Effects of Donepezil, Nicotine and Haloperidol on the Central Serotonergic System in Mice: Implications for Tourette Syndrome. Pharmacology, Biochemistry and Behavior; 81(4):879-886 (2005).

Hayslett, Renee and Tizabi, Yousef. Effects of Donepezil on DOI-induced Head Twitch Response in Mice: Implications for Tourette Syndrome. Pharmacology, Biochemistry and Behavior; 76(3-4):409-15 (2003).

Courses
PHA 440 General Principles of Pharmacotherapy
PHA 450 Nervous System Disorders I
PHA 556 Integument and Special Senses